Status:
ACTIVE_NOT_RECRUITING
Plasma Trimethylamine N-oxide Elevation Induced by L-carnitine Supplementation and Insulin Resistance
Lead Sponsor:
Poznan University of Physical Education
Conditions:
Insulin Resistance
Eligibility:
All Genders
20-30 years
Phase:
NA
Brief Summary
The primary aims of the current study: * using L-carnitine supplementation modulate the level of plasma trimethylamine N-oxide to assess its effect on circulating cytokines related to diabetes and me...
Detailed Description
Subjects will be randomly divided in two groups: supplemented by L-carnitine 2g/day for 12 weeks, and placebo group receiving leucine in identical gelatine capsules. Subjects who successfully complet...
Eligibility Criteria
Inclusion
- healthy volunteers,
- must be able to swallow tablets
Exclusion
- smokers,
- cardiovascular disease
- liver disease
- kidney disease
- gastrointestinal disorders (including stomach ulcers and erosions)
- diabetes
Key Trial Info
Start Date :
February 7 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 31 2027
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05251207
Start Date
February 7 2022
End Date
May 31 2027
Last Update
October 3 2025
Active Locations (1)
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1
Akademia Wychowania Fizycznego
Poznan, Poland, 61-871