Status:

UNKNOWN

Comparison of PD1+T Cell Expression in Peripheral Blood for Cardiac Function Prognosis in Patients With Acute MI

Lead Sponsor:

Second Affiliated Hospital, School of Medicine, Zhejiang University

Collaborating Sponsors:

First People's Hospital of Hangzhou

Conditions:

PD1

Acute Myocardial Infarction

Eligibility:

All Genders

18+ years

Brief Summary

Comparison of high PD1+ T cell and low PD1+ T cell expression in peripheral blood for cardiac function prognosis in Patients with acute myocardial infarction

Detailed Description

Myocardial infarction is a serious common disease in human beings. Although many patients with acute myocardial infarction survive with the improvement of medical technology in recent years, studies h...

Eligibility Criteria

Inclusion

  • Over 18 years of age;
  • Understand oral confirm to accept the risks and benefits of this experiment could bring He (she) or its legal representative in experiment related to provide written informed consent before surgery;
  • Was diagnosed with st-elevation acute myocardial infarction;
  • Based on the visual assessment of coronary angiography of coronary artery stenosis degree is 50% and the row stenting patients;
  • The target vessels are limited to the main coronary arteries (including the left anterior descending, left circumflex, and right coronary arteries).

Exclusion

  • Pregnant or lactating women; Patients with previous malignant tumors or mental diseases; Recent major trauma/trauma, or surgical treatment; Drug, drug and alcohol abusers; Those who have been receiving antitumor drugs, immunosuppressants, hormones and antibiotics for a long time; People with blood-borne infectious diseases (including hepatitis B, c, syphilis, AIDS, etc.);
  • People with immune deficiency diseases or autoimmune diseases; Liver and kidney dysfunction; Aortic dissection, pulmonary embolism, acute myocarditis or severe valvular disease; One who is in the acute phase of any illness (influenza, pneumonia, gastroenteritis, skin disease, etc.).

Key Trial Info

Start Date :

October 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 30 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT05251987

Start Date

October 1 2021

End Date

December 30 2022

Last Update

February 23 2022

Active Locations (1)

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The Second Affiliated Hospital of Zhejiang University, School of Medicine

Hangzhou, Zhejiang, China