Status:
UNKNOWN
Improving Cyberknife Spinal Stereotactic Radiotherapy in Difficult to Treat Cases (IMPRESS)
Lead Sponsor:
Royal Marsden NHS Foundation Trust
Conditions:
Solid Tumor, Adult
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
A prospective study evaluating prone and supine positioning for radiation planning of spine Cyberknife radiotherapy treatment. Patients with tumours in which PTV coverage is compromised due to tumour ...
Detailed Description
This is a prospective, non-randomised radiotherapy planning study. Subsets of patients with specific tumour and anatomical characteristics will benefit from improved PTV prescription isodose coverage...
Eligibility Criteria
Inclusion
- • Patients undergoing Cyberknife treatment to spinal metastasis
- \>18 years of age
- Thoracic, lumbar and sacral spinal metastasis
- Patients suitable to undergo radiotherapy planning CT scans in the prone position (treating physician assessed as having spinal stability).
- All solid tumour types will be eligible
Exclusion
- • Primary spinal tumours
- Vertebral disease resulting in unstable spinal vertebrae
- Cervical tumours (patients will be unable to have a thermoplastic shell made for the prone position).
- Patients with significant pain on prone lying (to be assessed by physician prior to consent)
- Bilsky epidural score of 2 or greater (see appendix 1)
- Pre-existing musculoskeletal chronic back medical diagnoses that would preclude CT scanning in the prone position.
Key Trial Info
Start Date :
July 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2023
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT05252975
Start Date
July 1 2020
End Date
April 1 2023
Last Update
February 23 2022
Active Locations (1)
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1
Royal Marsden NHS Foundation Trust
Sutton, Surrey, United Kingdom, SM2 5PY