Status:
COMPLETED
Impact of Intracoronary Versus Intravenous Epinephrine Administration During Cardiac Arrest .
Lead Sponsor:
Lithuanian University of Health Sciences
Collaborating Sponsors:
Baylor Scott and White Health
Minneapolis Heart Institute
Conditions:
Cardiopulmonary Arrest
Epinephrine Causing Adverse Effects in Therapeutic Use
Eligibility:
All Genders
18+ years
Brief Summary
In hospital cardiac arrest (IHCA) is a major challenge imposed on almost all health care systems worldwide. Despite significant progress in cardiopulmonary resuscitation in the past few years, outcome...
Eligibility Criteria
Inclusion
- Aged above 18 years old
- Diagnosed with non-ST elevation myocardial infarction (NSTEMI) or ST elevation myocardial infarction (STEMI)
- Received dual antiplatelet therapy (acetylsalicylic acid and ticagrelor), or triple therapy (oral anticoagulant, acetylsalicylic acid and clopidogrel)
- Event of cardiac arrest during percutaneous intervention
Exclusion
- cardiac arrest documented prior to being transported to cardiac catheterization laboratory.
- Patients who suffered cardiac arrest for less than 60 seconds were excluded from the study.
- Received mechanical circulatory support such as intra-aortic balloon pump, temporary percutaneous ventricular assist devices, or extracorporeal membrane oxygenation (ECMO) during hospitalization.
- Presenting with any cardiac rhythm on admission other than sinus rhythm or atrial fibrillation/flutter
- Signs of infection or a history of hepatic, oncologic or allergy to contrast media and end stage renal failure
- Patients who underwent primary fibrinolysis.
- Furthermore, patients who received atropine, amiodarone, lidocaine, or any other antiarrhythmic prior to CPR
- who received targeted temperature management post CPR .
Key Trial Info
Start Date :
April 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2022
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT05253937
Start Date
April 1 2018
End Date
June 1 2022
Last Update
August 16 2022
Active Locations (1)
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1
Ali Aldujeli
Kaunas, Lithuania, LT-50161