Status:
COMPLETED
taVNS Cold Pressor
Lead Sponsor:
Medical University of South Carolina
Collaborating Sponsors:
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
Conditions:
taVNS
Brain Stimulation
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
This study explores the use of transcutaneous auricular vagus nerve stimulation (taVNS), a new form of neuromodulation which stimulates the ear. 24 healthy subjects without a past medical or psychiatr...
Eligibility Criteria
Inclusion
- Ages 18-65 years
- English speaking
- Non-treatment-seeking community members
Exclusion
- Diagnosis of COVID-19 in the past 14 days
- Facial or ear pain or recent ear trauma.
- Metal implant devices in the head, heart or neck.
- History of brain stimulation or other brain surgery.
- History of myocardial infarction or arrhythmia, bradycardia.
- Use of B-blockers, antiarrhythmic medication (sodium/potassium/calcium-channel blockers), or blood pressure medications.
- Active respiratory disorder.
- Personal or family history of seizure or epilepsy or personal use of medications that substantially reduce seizure threshold (e.g., olanzapine, chlorpromazine, lithium).
- Personal history of head injury, concussion, or self-report of moderate to severe traumatic brain injury.
- Individuals suffering from frequent/severe headaches.
- Individuals with a reported history of any mental health disorder or taking any psychotropic medications.
- Moderate to severe alcohol or substance use disorder.
- Pregnancy
Key Trial Info
Start Date :
October 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 20 2021
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT05254080
Start Date
October 1 2021
End Date
December 20 2021
Last Update
January 17 2024
Active Locations (1)
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1
Medical University of South Carolina
Charleston, South Carolina, United States, 29425