Status:
RECRUITING
Using Micro-filaments to Detect "fast Ripples" and Improve the Identification of the Epileptogenic Zone
Lead Sponsor:
Adrien Peyrache
Conditions:
Epilepsy, Refractory
Eligibility:
All Genders
Phase:
NA
Brief Summary
record fast ripples with novel intracranial electrodes with micro-tetrodes to improve the identification of epileptogenic zone (EZ) and investigate the neuronal circuits underlying brain dynamics asso...
Detailed Description
This study would improve the localization of the epileptogenic zone and reduce the overall duration of monitoring, especially in patients who do not experience a sufficient number of seizures during t...
Eligibility Criteria
Inclusion
- inclusion criteria is determined based on the clinical diagnosis of the refractory epilepsy and the admissibility of the patient for the stereoelectroencephalography (sEEG) procedure
Exclusion
- severe psychiatric disorders,
- severe agitation during their crisis
- contraindication for performing an MRI: claustrophobia, a cardiac or neural stimulator, ferromagnetic surgical clips, cochlear implants, intraocular metallic foreign body or in the nervous system,
- contraindication to intracerebral investigation (macro-electrodes): ongoing infection, severe associated pathology (cardiac, pulmonary, renal, hepatic), pregnant or nursing women,
- anti thrombotic ongoing treatment.
Key Trial Info
Start Date :
September 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2028
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT05254730
Start Date
September 1 2023
End Date
December 30 2028
Last Update
November 20 2024
Active Locations (1)
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1
McGill University
Montreal, Quebec, Canada, H3A 2B4