Status:
ENROLLING_BY_INVITATION
Exercise Intervention in Patients With Heart Failure With Preserved and Reduced Ejection Fraction
Lead Sponsor:
Region Skane
Conditions:
Heart Failure New York Heart Association (NYHA) Class II
Heart Failure New York Heart Association (NYHA) Class III
Eligibility:
All Genders
50-90 years
Phase:
NA
Brief Summary
The objective of this study is to assess by what physiological mechanisms patients with heart failure benefit from exercise. Effects of an exercise intervention will be assessed for both central (hear...
Detailed Description
A randomized, non-blinded prospective intervention trial. Patients randomized to exercise intervention will undergo supervised aerobic training on ergometer cycle for 12 weeks whilst control group rec...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Signs and symptoms of heart failure
- Age ≥50 years
- Stable chronic heart failure (no hospitalizations within past month, no new medications past month)
- Able to understand and follow exercise prescription
- Currently physically inactive (less than 150 minutes/week moderate intensity exercise)
- Exclusion criteria:
- Currently or within the past 6 months been involved in cardiac rehab with exercise
- Devices or implants not compatible with magnetic resonance imaging or exercise testing
- Any orthopedic or medical condition affecting participation in testing and training
- Signs of acute ischemia during baseline cardiopulmonary exercise testing
- Participation in other clinical trials that may affect results
- Moderate or severe valvular disease
- Atrial fibrillation
- Moderate or severe chronic obstructive pulmonary disease
- NYHA class IV
Exclusion
Key Trial Info
Start Date :
June 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT05255172
Start Date
June 1 2022
End Date
December 31 2027
Last Update
June 29 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Skåne University Hospital Lund
Lund, Sweden, 22158