Status:

COMPLETED

Epicardial Stimulation of the Cardiac Autonomic Nervous System

Lead Sponsor:

Rennes University Hospital

Conditions:

Cardiac Insufficiency

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The objective of the EpiCANS study is to evaluate the technique of stimulation of the cardiac autonomic nervous system (SNAC) directly at the epicardial level in humans during heart surgery. Proof of...

Detailed Description

Isolated stimulation of the parasympathetic system induces a protective effect on long-term cardiac remodeling, but at the cost of inhibiting the sympathetic system. The role of the sympathetic system...

Eligibility Criteria

Inclusion

  • Scheduled for elective cardiac surgery for valvular or coronary surgery
  • Having received written and oral information about the protocol and having signed a written informed consent
  • Affiliated or beneficiary of a social security plan

Exclusion

  • Patient with an indication for cardiac surgery:
  • Urgent or semi-urgent
  • Aortic surgery
  • Heart transplantation
  • Mechanical circulatory assistance
  • Patients who have already undergone cardiac surgery
  • Adults under legal protection (safeguard of justice, curatorship, guardianship), persons deprived of liberty, pregnant or breastfeeding women, minors, persons unable to express their consent, persons hospitalized for a different reason

Key Trial Info

Start Date :

August 16 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 13 2023

Estimated Enrollment :

4 Patients enrolled

Trial Details

Trial ID

NCT05255952

Start Date

August 16 2022

End Date

November 13 2023

Last Update

September 27 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

CHU Rennes

Rennes, France, 35033

Epicardial Stimulation of the Cardiac Autonomic Nervous System | DecenTrialz