Status:
UNKNOWN
HAPPCAP-AD (Human-APPlication Combined Approach for Prevention of Alzheimer's Disease)
Lead Sponsor:
Sheba Medical Center
Collaborating Sponsors:
Maccabi Healthcare Services, Israel
Conditions:
Alzheimer Disease
Eligibility:
All Genders
40-65 years
Phase:
NA
Brief Summary
Currently, Alzheimer's disease (AD) has no cure putting prevention-strategies in the forefront for impeding the public health and personal consequences of this devastating disease. Seven major potenti...
Detailed Description
To examine the feasibility and provide pilot data on effectiveness of a novel "real-life" personalized 18-months intervention for prevention of cognitive decline in middle-aged individuals (age 40-65-...
Eligibility Criteria
Inclusion
- • Age 40-65 at enrollment to the study
- Family history of AD-All subjects recruited will have at least 1 parent diagnosed with AD (as specified below)
- All participant will be MHS (Maccabi Health System) members
- Participants must have at least two of the seven risk factors for AD (1. Smoking; 2. type 2 diabetes \[T2D\]; 3. Hypertension; 4. obesity/ overweight; 5. low physical inactivity; 6. low educational attainment/ mental activity; 7. depression)
- No dementia diagnosis
- Hebrew fluency
Exclusion
- Previously diagnosed dementia•
- Any condition expected to limit the adherence to suggested intervention for 18 months
- Any significant neurologic or psychiatric disease
Key Trial Info
Start Date :
June 4 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT05256121
Start Date
June 4 2019
End Date
December 31 2024
Last Update
May 24 2022
Active Locations (1)
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1
Sheba Medical Center
Ramat Gan, Israel, 52621