Status:

RECRUITING

Cortical Excitability in Cyclic Vomiting Syndrome

Lead Sponsor:

University of Pittsburgh

Conditions:

Cyclic Vomiting Syndrome

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

This exploratory study will determine if there are differences in cortical excitability between patients suffering from cyclic vomiting syndrome (CVS) and healthy control subjects, as assessed by a no...

Detailed Description

This exploratory study will determine if there are differences in cortical excitability between patients suffering from cyclic vomiting syndrome (CVS) and healthy control subjects, as assessed by a no...

Eligibility Criteria

Inclusion

  • diagnosis of CVS

Exclusion

  • history of CVS (for healthy control population only)
  • psychosis or altered cognitive status
  • history of head injury, metal in the skull, stroke, or a history of seizures or a history of syncope (fainting or passing out)
  • implantable devices, such as a pacemaker or nerve stimulator
  • current use of the following medications or use of substances which are known to lower the seizure threshold: clozapine (Clozaril), chlorpromazine (Thorazine), amphetamines or methamphetamine, Ecstasy, Ketamine, Angel Dust/PCP, cocaine, or 3 or more alcoholic drinks per day
  • pregnancy

Key Trial Info

Start Date :

May 16 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2027

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT05256160

Start Date

May 16 2022

End Date

June 1 2027

Last Update

August 24 2025

Active Locations (1)

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1

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States, 15232