Status:

ACTIVE_NOT_RECRUITING

Factors Influencing Breast Cancer Resection Volumes And Their Impact on Treatment Outcome (FIBRATIO)

Lead Sponsor:

Tampere University Hospital

Collaborating Sponsors:

Jyväskylä Central Hospital

Turku University Hospital

Conditions:

Breast Cancer

Quality of Life

Eligibility:

FEMALE

18-80 years

Brief Summary

The number of breast cancer survivors is constantly growing. Breast conserving surgery (BCS) is equal or superior to mastectomy both regarding survival and quality of life (QoL). Hence, as many patien...

Detailed Description

1. Background Breast cancer is the most common cancer worldwide. The prognosis of early-stage breast cancer is good - more than 90 % of the patients are alive five years after diagnosis. Since man...

Eligibility Criteria

Inclusion

  • primary, solitary/multifocal, unilateral cTis-T2 breast cancer eligible for BCS
  • DCIS, ductal, lobular and other subtypes of invasive breast cancer (excluding LCIS and ADH)
  • ASA 1-2 and life expectancy more than 3 years
  • mammogram done with a device showing compression thickness
  • no previous breast surgery (bilateral reduction mammoplasty or mastopexy accepted)

Exclusion

  • metastatic breast cancer
  • previous ipsi- or contralateral breast cancer
  • bilateral breast cancer
  • hereditary breast cancer
  • contralateral symmetrization procedure in conjunction with the cancer surgery
  • contraindication for radiotherapy
  • neoadjuvant treatment
  • pregnancy or breastfeeding
  • inability to provide informed consent

Key Trial Info

Start Date :

May 28 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 30 2027

Estimated Enrollment :

220 Patients enrolled

Trial Details

Trial ID

NCT05257577

Start Date

May 28 2022

End Date

March 30 2027

Last Update

April 24 2024

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Hospital Nova of Central Finland

Jyväskylä, Finland, 40620

2

Kuopio University Hospital

Kuopio, Finland, 70210

3

Tampere University Hospital

Tampere, Finland

4

Turku University Hospital

Turku, Finland