Status:
RECRUITING
Exploring Cortical Remyelination in Children With Multiple Sclerosis
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Children With Multiple Sclerosis
Eligibility:
All Genders
12-18 years
Phase:
NA
Brief Summary
Multiple sclerosis (MS) in children, a rare disease, follows a relapsing remitting course with a shorter interval between the first 2 clinical events and higher annualized relapse rate as compared wit...
Detailed Description
Multiple sclerosis (MS) in children, a rare disease, follows a relapsing remitting course with a shorter interval between the first 2 clinical events and higher annualized relapse rate as compared wit...
Eligibility Criteria
Inclusion
- Inclusion Criteria for patients :
- age between 12 years old and 18 years old
- RR-MS defined by 2017 McDonald criteria
- no relapse the last 4 weeks
- no methylprednisolone or prednisolone the last 4 weeks.
- affiliated to the social security system
- signature of the consent by the 2 holders of parental authority
- Inclusion Criteria for Volunteers:
- age between 12 years old and 18 years old
- absence of any neurological
- signature of the consent by the 2 holders of parental authority
- Exclusion Criteria for both groups:
- Parental rejection
- Contre-indication of brain MRI: pace maker, tatoo of the face, claustrophobia….
- Pregnancy, copper intrauterine device
Exclusion
Key Trial Info
Start Date :
August 11 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 11 2025
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05258396
Start Date
August 11 2022
End Date
September 11 2025
Last Update
September 4 2025
Active Locations (3)
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1
Service de Neurologie Pédiatrique, Hôpital du Kremlin Bicêtre
Le Kremlin-Bicêtre, France, 94270
2
CIC Neurosciences - Pitié Salpêtrière
Paris, France, 75013
3
Service de Neurologie, GH Pitié Salpêtrière
Paris, France, 75013