Status:
COMPLETED
Morphine vs Sufentanil PCA: Same Same or Different?
Lead Sponsor:
Hospital Central do Funchal
Conditions:
Analgesia
Post Operative Pain
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Patient-controlled intravenous analgesia (PCA) has already proven its quality. However, with new strategies starting to emerge and the current concept of opioid sparing, it is a goal to find the optim...
Detailed Description
In a prospected randomized study, it was compared the use of Sufentanil Sublingual PCA System (15mcg per tablet, 20 minutes lockout) with intravenous PCA Morphine based on 1mg morphine on-demand 10 mi...
Eligibility Criteria
Inclusion
- Informed consent signed;
- Age superior to 18 years;
- Physical status according to the American Society of Anesthesiology (ASA) 1-3;
- Scheduled gynecological surgery: abdominal hysterectomy
- Scheduled orthopedic surgery: total knee arthroplasty or total hip arthroplasty.
Exclusion
- Patient refusal to participate in the study;
- Age \<18 years or legal dependence;
- Neurological or psychiatric pathology or altered state of consciousness that does not allow for the Patient Controlled Analgesia strategy;
- Documented drinking habits and/or consumption of illicit drugs;
- Patients tolerant to opioid therapy (use of \>15 mg oral morphine or its equivalent per day for the last 3 months);
- Documented obstructive Sleep Apnea Syndrome (OSAS);
- Patients on long-term oxygen therapy;
- Intraoperative use of intrathecal morphine;
- Use of anesthetic techniques in order to provide postoperative analgesia (eg, epidural catheter; peripheral nerve block; infiltration of the surgical wound with local anesthetic).
Key Trial Info
Start Date :
October 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 31 2020
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT05259098
Start Date
October 1 2019
End Date
October 31 2020
Last Update
February 28 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Hospital Central do Funchal
Funchal, Madeira, Portugal, 9000-177