Status:

ACTIVE_NOT_RECRUITING

Collaborative Approach to Examining Adversity and Building Resilience Study

Lead Sponsor:

University of California, San Francisco

Collaborating Sponsors:

Lifelong Medical Care

UCSF Benioff Children's Hospital Oakland

Conditions:

Early Life Adversity

Caregiver Stress

Eligibility:

All Genders

2+ years

Phase:

NA

Brief Summary

To examine the behavioral, psychosocial, and biologic impact of resilience-promoting interventions associated with primary care.

Detailed Description

Early-life trauma and related adversities are prevalent and associated with negative health and achievement outcomes. These adverse childhood experiences (ACEs) are especially common in economically d...

Eligibility Criteria

Inclusion

  • Regular access to web-based computer, smart phone, or tablet if necessary to delivery via telehealth due to the COVID19 Pandemic (relative exclusion criteria - have budgeted to provide tablets and mobile wifi hot spots for up to 10% of participants)
  • Attachment and Biobehavioral Catch-up (ABC) Program
  • Caregiver: 18 years old and older, primary caregiver, English or Spanish speaking
  • Child: 2 to 4 years, PEARLS score \> 1
  • Resilience Clinic
  • Caregiver: 18 years old and older, primary caregiver, English or Spanish speaking
  • Child: 2 to 5 years, PEARLS score \> 1 or verbal disclosure of PEARLS adversity to primary care clinician/staff
  • HEROES Family Program
  • Caregiver: 18 years old and older, primary caregiver, ACE score \> 2 if child PEARLS score = 0, English or Spanish speaking
  • Child: 2 to 5 years, PEARLS score \> 1

Exclusion

  • Caregiver: active suicidality, other psychiatric issues
  • Child: significant medical co-morbidities (i.e. disease requiring immunomodulators, chemo or radiation therapy, or hormonal therapy)

Key Trial Info

Start Date :

April 11 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2025

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT05259436

Start Date

April 11 2022

End Date

June 30 2025

Last Update

May 8 2025

Active Locations (4)

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Page 1 of 1 (4 locations)

1

UCSF Benioff Children's Hospital Oakland

Oakland, California, United States, 94609

2

LifeLong Medical Care

Richmond, California, United States, 94804

3

Zuckerberg San Francisco General Hospital and Trauma Center

San Francisco, California, United States, 94110

4

Santa Barbara Neighborhood Clinics

Santa Barbara, California, United States, 93101