Status:
RECRUITING
Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification
Lead Sponsor:
European Organisation for Research and Treatment of Cancer - EORTC
Conditions:
Glioma
Glioneuronal Tumor
Eligibility:
All Genders
18+ years
Brief Summary
Every new classification depends on its prognostic power and on the type of treatment given. With the rapid evolution of diagnostic methods and the advance in new treatments, there is much less reliab...
Eligibility Criteria
Inclusion
- Age ≥ legal age of consent
- Newly diagnosed or recurrent primary brain tumours within one of the 17 cohorts of interest
- Archival tumour tissue from primary tumour available at the site. Representative tissue from first surgery is preferred, but tissue from surgery for recurrence is allowed. Exception: only tissue from first surgery is allowed for Cohort 16.
- Available MRI/CT scans from primary brain tumour at initial diagnosis
- Patient's consent
- Deceased patient:
- The clinical data and/or biological material and/or CT/MRI/PET images can be accessed and used if at least one of the following three conditions is met:
- The patient agreed beforehand in his/her lifetime to a further use of his/her data and/or biological material and/or CT/MRI/PET images, or,
- There is consent of a relative to use data and/or biological material and/or CT/MRI/PET images of the deceased patient, or,
- There is a reference to a corresponding legal declaration covering the exemption in case of the impossibility or disproportion of getting access to an informed consent (e.g., causing strain on relatives of deceased patients).
- Additionally, in all cases the following three points need to be fulfilled:
- No documentation of previous objection of the patient to the (re-)use of their data, biological material, CT/MR/PET images for research purposes
- A notification to an ethics committee for the re-use of these data, biological material and CT/MRI/PET images
- Any other national requirements are fulfilled, if applicable
Exclusion
Key Trial Info
Start Date :
March 21 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 29 2038
Estimated Enrollment :
1650 Patients enrolled
Trial Details
Trial ID
NCT05259605
Start Date
March 21 2023
End Date
July 29 2038
Last Update
December 17 2025
Active Locations (42)
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1
Innsbruck Universitaetsklinik
Innsbruck, Austria
2
Universitaetsklinikum Wien - AKH unikliniken
Vienna, Austria
3
Onze Lieve Vrouw Ziekenhuis
Aalst, Belgium
4
Institut Jules Bordet
Anderlecht, Belgium