Status:
UNKNOWN
Next Generation Sequencing to Detect Acute Rejection in Lung Transplant Patients.
Lead Sponsor:
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Collaborating Sponsors:
University of Milan
Conditions:
Lung Transplant Rejection
Eligibility:
All Genders
18-65 years
Brief Summary
Lung transplantation is a consolidated treatment in selected patients with end-stage respiratory diseases; however, acute rejection remains an important cause of lung allograft loss and a risk factor ...
Detailed Description
The purpose of the study is the identification of a non-invasive post-transplantation acute lung rejection monitoring method, by identification of donor derived cell free DNA (ddcf-DNA) in the recipie...
Eligibility Criteria
Inclusion
- Patients undergoing lung transplantation at our centre
- Patients aged 18 to 65 years old
- Written informed consent to partecipate in the study
Exclusion
- Patients undergoing retransplantation
- Patients with a history of prior solid organ transplantation
Key Trial Info
Start Date :
October 4 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2022
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT05260372
Start Date
October 4 2018
End Date
December 1 2022
Last Update
March 2 2022
Active Locations (1)
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1
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy, 20122