Status:

COMPLETED

Effects of Caffeine on Anxiety, Emotional Processing, Approach-avoidance Behavior, and Interoception in Panic Disorder

Lead Sponsor:

Uppsala University

Conditions:

Panic Disorder

Healthy

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The current study is a placebo-controlled, double-blind, randomized controlled study using a cross-over design, including participants with Panic disorder and healthy controls. The study's primary ai...

Detailed Description

Hypotheses Self-reported anxiety during resting state * Participants with Panic disorder will report higher resting-state levels of anxiety and negative emotions during the caffeine condition vs the...

Eligibility Criteria

Inclusion

  • Panic disorder group: Primary diagnosis of panic disorder.
  • Healthy control group: No current or history of psychiatric disorders.
  • All participants (Panic disorder and healthy): Weekly caffeine consumption ≤ 300 mg.

Exclusion

  • History of severe psychiatric disorder (e.g. schizophrenia). Somatic or neurological conditions (e.g. hypertension and heart condition). Ongoing treatment with psychotropic medication or treatment with psychotropic medication which has been discontinued within 2 months. Other ongoing treatments that may confound the results. Current drug or alcohol abuse/dependency. Habitual nicotine use. Uncorrected visual or hearing impairment. Pregnancy.

Key Trial Info

Start Date :

March 16 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 19 2023

Estimated Enrollment :

83 Patients enrolled

Trial Details

Trial ID

NCT05261594

Start Date

March 16 2022

End Date

March 19 2023

Last Update

April 19 2023

Active Locations (1)

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Uppsala university, Department of Medical Sciences, Psychiatry

Uppsala, Sweden, 75185