Status:
RECRUITING
Diffusion MRI of the Abdomen
Lead Sponsor:
University of Wisconsin, Madison
Collaborating Sponsors:
National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Conditions:
Abdominal Imaging
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this research is to see if a new magnetic resonance imaging (MRI) method will be able to improve the images taken of the abdomen. This new method includes some changes to help avoid mov...
Detailed Description
This study will develop and validate novel DW-MRI methods with unprecedented robustness to motion, favorable image quality, and quantitative precision for abdominal imaging. Upon successful completion...
Eligibility Criteria
Inclusion
- Inclusion Criteria for Healthy Volunteers:
- 18 years of age or older
- Exclusion Criteria for Healthy Volunteers:
- Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc)
- Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening)
- Inclusion Criteria for Patients:
- 18 years of age or older
- Patients with at least one of the following:
- Radiologically visible solid tumor liver metastasis, with at least one metastatic liver lesion must be a minimum of 8 mm in longest diameter
- Patients presenting for liver lesion biopsy
- Exclusion Criteria for Patients:
- Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc)
- Patients with known contraindication to GBCA such as severe kidney disease or previously documented GFR \< 30 ml/min/1.73 m2
- Patients requiring intravenous (IV) conscious sedation for imaging are not eligible; patients requiring mild, oral anxiolytics for the MRI will be allowed to participate as long as the following criteria are met:
- The subject has their own prescription for the medication.
- The informed consent process is conducted prior to the self-administration of this medication
- They come to the research visit with a driver
- Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening)
- Stent in bile ducts
- Partial hepatectomy
Exclusion
Key Trial Info
Start Date :
November 22 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2026
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT05261633
Start Date
November 22 2023
End Date
June 30 2026
Last Update
November 12 2025
Active Locations (1)
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1
University of Wisconsin School of Medicine and Public Health
Madison, Wisconsin, United States, 53792