Status:
COMPLETED
Effect of Smoking on Periodontal Therapy in Periodontitis
Lead Sponsor:
Marmara University
Conditions:
Periodontal Diseases
Smoking
Eligibility:
All Genders
24-56 years
Phase:
NA
Brief Summary
The present study aimed to assess the effect of smoking on non-surgical periodontal treatment on serum and salivary RANKL, OPG and IL34 levels in periodontitis stage III grade C (P-III-C) patients. 20...
Detailed Description
Periodontal disease is an inflammatory process that can result in tooth loss and also is considered a modifying factor for systemic health. In bone tissue, bone resorption by osteoclasts and bone form...
Eligibility Criteria
Inclusion
- systemically healthy individuals
- having ≥20 teeth present (except third molars)
- individuals with periodontally healthy, periodontitis stage III grade C diagnoses
- Smokers were smoking 10 cigarettes per day more than 5 years while non-smokers were never smoked.
Exclusion
- having any diagnosed medical disorders such as diabetes mellitus, cardiovascular diseases, rheumatoid arthritis, immunological and mucocutaneous diseases
- usage of antibiotics, non-steroidal anti-inflammatory drugs and immunosuppressive agents within the past 6 months
- having any non-inflammatory destructive periodontal disease
- nonsurgical/surgical periodontal therapy received in the past year
- pregnant/ lactating/ postmenopausal females.
Key Trial Info
Start Date :
January 25 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 15 2020
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05262153
Start Date
January 25 2019
End Date
September 15 2020
Last Update
March 2 2022
Active Locations (1)
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1
Marmara University, Faculty of Dentistry, Department of Periodontology
Istanbul, Turkey (Türkiye)