Status:

COMPLETED

Targeted Fluorescence Imaging in AMD

Lead Sponsor:

University Medical Center Groningen

Conditions:

Age-Related Macular Degeneration

NAMD

Eligibility:

All Genders

60+ years

Phase:

PHASE1

Brief Summary

Rationale: To track performance of intravitreal distribution of anti-VEGF-A (Bevazicumab-800CW) and provide information about neovascularization and inflammation in Age-Related Macular Degeneration (...

Eligibility Criteria

Inclusion

  • Patients with either naïve wet AMD or wet AMD receiving standard care of anti-VEGF therapy
  • Aged \>60 years old
  • Optional: Patients already included in fluorescence study which involves Bevacizumab-800CW

Exclusion

  • Eye pathology interfering with retinal imaging;
  • Patients with psychological diseases or medical issues who are not able to sign informed consent form;
  • Concurrent uncontrolled medical conditions;
  • Received a different investigational drug within 30 days prior to the dose of bevacizumab-800CW;
  • History of infusion reactions to bevacizumab or other monoclonal antibody.

Key Trial Info

Start Date :

October 28 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 30 2024

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT05262244

Start Date

October 28 2022

End Date

March 30 2024

Last Update

December 6 2024

Active Locations (1)

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1

University medical center Groningen (UMCG)

Groningen, Provincie Groningen, Netherlands, 9713 GZ