Status:
ACTIVE_NOT_RECRUITING
Developing mHealth to Promote PrEP Use Among Thai Young Vulnerable Adolescents and Emerging Adults
Lead Sponsor:
University of Massachusetts, Worcester
Collaborating Sponsors:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Wayne State University
Conditions:
Pre-Exposure Prophylaxis
Eligibility:
MALE
16-29 years
Phase:
NA
Brief Summary
The main aim of this study is to develop technology-based interventions to improve HIV pre-exposure prophylaxis (PrEP) uptake and adherence among Thai young transgender women.
Detailed Description
Motivational Enhancement System for Adherence (MESA) is a computer-based motivation invention, based on the Information-Motivation-Behavioral Skills (IMB) model and Motivational Interviewing (MI) prin...
Eligibility Criteria
Inclusion
- Aim 1:
- Transgender women participants
- Age 16-29 years old
- Male sex at birth
- Self-identifies as woman or transgender women or culturally identifies with the female spectrum
- Confirmed HIV-negative status
- Self-reported recent history of condomless sex in the past 6 months
- Able to understand, read and speak Thai
- Either having not started PrEP (Group 1: PrEP naive), currently on PrEP but not adherent to PrEP (taking ≤3 pills/week) in the past month (Group 2: PrEP users) or currently on PrEP with good adherence (Group 3: PrEP users with good adherence).
Exclusion
- Have a serious cognitive or psychiatric problem that would compromise ability to provide informed consent
- Have active suicidal ideation or major mental illness (e.g., untreated psychosis or mania) at the time of interview (patients will be referred for treatment)
- Laboratory or clinical findings that would preclude PrEP initiation (e.g., decreased creatinine clearance)
- Healthcare providers
- Inclusion Criteria:
- Have at least 1-year experience working with HIV-negative transgender women, including providing PrEP prescription and counseling
Key Trial Info
Start Date :
December 27 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2026
Estimated Enrollment :
145 Patients enrolled
Trial Details
Trial ID
NCT05262426
Start Date
December 27 2021
End Date
July 31 2026
Last Update
September 8 2025
Active Locations (3)
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1
Rainbow Sky Association of Thailand
Bangkok, Bangkok, Thailand, 10240
2
Institute of HIV Research and Innovation
Bangkok, Bangkok, Thailand, 10330
3
SWING Foundation
Bangkok, Bangkok, Thailand, 10500