Status:

COMPLETED

The Difference of Grey Matter Volume Among the Patients of Schizophrenia

Lead Sponsor:

Shanghai Mental Health Center

Conditions:

Schizophrenia

Neuroimaging

Eligibility:

All Genders

18-60 years

Brief Summary

Schizophrenia is a heritable complex phenotype whose symptoms can be clustered into three domains: positive symptoms, negative symptoms and cognitive impairments. Constellations of negative symptoms i...

Detailed Description

Schizophrenia (SCZ) is a heritable complex phenotype whose symptoms can be clustered into three domains: positive symptoms, negative symptoms and cognitive impairments. Constellations of negative symp...

Eligibility Criteria

Inclusion

  • All the patients satisfied the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-Ⅳ) diagnostic criteria for schizophrenia or schizophreniform disorder.
  • Women and men
  • 18 to 60 years of age
  • Able and willing to provide written informed consent; and willing to commit to the study protocol
  • Able to read, speak, and understand Chinese

Exclusion

  • (i) were \<18 years or \>60 years
  • (ii) psychotic patients in unstable clinical condition (e.g., being aggressive and uncooperative)
  • (iii) had major neurological or other psychiatric disorders, or significant medical condition including neurological disease, severe cardiovascular, hepatic, renal diseases
  • (iv)had MRI abnormalities, or had MRI contraindications.

Key Trial Info

Start Date :

June 26 2013

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2017

Estimated Enrollment :

253 Patients enrolled

Trial Details

Trial ID

NCT05262790

Start Date

June 26 2013

End Date

January 1 2017

Last Update

March 2 2022

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