Status:

UNKNOWN

The Function of PET Molecular Imaging Targeting Fibroblast Activation Protein in the Hepatobiliary Malignancies

Lead Sponsor:

Zhongnan Hospital

Conditions:

Hepatobiliary Diseases

Eligibility:

All Genders

18-80 years

Brief Summary

Patients with high clinical suspicion of hepatobiliary malignancies should undergo PET/CT examination with two imaging agents, 68Ga-FAPI (fibroblast activation protein inhibitor) and 18F-FDG within on...

Detailed Description

Patients with high clinical suspicion of hepatobiliary malignancies should undergo PET/CT examination with two imaging agents, 68Ga-FAPI (fibroblast activation protein inhibitor) and 18F-FDG within on...

Eligibility Criteria

Inclusion

  • Voluntarily participate and sign a written informed consent;
  • 18-80 years old (inclusive) male or female;
  • Patients with high clinical suspicion of hepatobiliary malignancy in combination with medical history and imaging studies, etc.
  • Those who obtained pathological diagnosis results through needle biopsy or surgical resection;
  • Have willingness and ability to participate in all research procedures.

Exclusion

  • Women who are pregnant or breastfeeding;
  • Those who are known to be allergic to the imaging agent 68Ga-FAPI or its excipients;
  • Those who have a history of other malignant tumors in the past;
  • Before the injection of 18F-FDG, the fasting blood glucose level exceeds 11.0mmol/L;
  • Patients with claustrophobia;
  • Those who cannot tolerate lying down for 15-30 minutes;
  • The researchers believe that it is not suitable to participate in this clinical trial;
  • Those who have participated in clinical trials or are participating in other clinical trials within the past month

Key Trial Info

Start Date :

January 20 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 31 2022

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT05264688

Start Date

January 20 2022

End Date

October 31 2022

Last Update

April 27 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Zhongnan Hospital

Wuhan, Hubei, China, 430000

The Function of PET Molecular Imaging Targeting Fibroblast Activation Protein in the Hepatobiliary Malignancies | DecenTrialz