Status:
COMPLETED
The Effect of Sleep Apnea and Hypertension on Gut Microbiome
Lead Sponsor:
Peking University First Hospital
Conditions:
Obstructive Sleep Apnea
Hypertension
Eligibility:
All Genders
18+ years
Brief Summary
Obstructive sleep apnea (OSA) and hypertension are closely associated diseases. Here we characterized the differences in the gut microbiome which is affected by the two diseases, when the two diseases...
Detailed Description
1. Participants Participants who underwent overnight polysomnography (PSG) in the sleep laboratory of Peking University First Hospital from July 2017 to November 2017 were included in the study. This ...
Eligibility Criteria
Inclusion
- age 18 years or older
- outpatients and inpatients who underwent a PSG study for snoring
- those who volunteered for this study and signed an informed consent form
Exclusion
- patients who were treated for OSA (regular CPAP therapy, oral appliances, maxillofacial surgery, etc.) prior to enrolment
- patients with secondary HT with a clear primary cause
- those with a history of dyspeptic disease (history of gastrointestinal surgery, peptic ulcer, inflammatory bowel disease, chronic pancreatitis, etc.)
- those who had organ insufficiency, were receiving immune agents or glucose
- those who had received antibiotic treatment in the last 2 months or had taken probiotic products (yogurt, milk, cheese, etc.) continuously (daily) for the last 2 months
- Alcohol or drug dependency
Key Trial Info
Start Date :
July 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 28 2018
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT05266131
Start Date
July 1 2017
End Date
May 28 2018
Last Update
October 22 2024
Active Locations (1)
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1
Peking University First Hospital
Beijing, Beijing Municipality, China, 100034