Status:

COMPLETED

Revascularisation of Autotransplanted Teeth

Lead Sponsor:

Medical University of Graz

Conditions:

Endodontic Disease

Pulp Canal Obliteration

Eligibility:

All Genders

12-70 years

Phase:

NA

Brief Summary

Retrospective Analysis of a Study cohort that experienced autotransplantation of mature teeth with simultaneous root end resection Note: The study was registered on Clinicaltrials.gov after terminati...

Eligibility Criteria

Inclusion

  • Male and female consenting and judicious young people and adults
  • Written consent of the participant and, if applicable, of the legal guardian after education
  • Planned tooth transplantation with advanced or completed root growth

Exclusion

  • Contraindications for magnetic resonance imaging (MRI): (pronounced metal restorations, running orthodontics with metal, fixed appliance in the target jaw)
  • Current or past antiresorptive therapy with bisphosphonates
  • Further anamnestic general or local risk situation, among others: Anti-angiogenic therapy, History of local radiation therapy, severe coagulation disorder, unadjusted diabetes mellitus, malignant diseases
  • Acute gingivitis or advanced periodontitis
  • Participation in an ongoing drug trial (various drugs may distort the result, such as bisphosphonates, cortisone, chemotherapeutics, angiogenesis inhibitors)
  • heavy smokers (\> 10 per day)
  • Acute or chronic infections (osteomyelitis) at the surgical site
  • metabolic diseases (diabetes, hyperparathyroidism, osteomalacia)
  • Severe kidney dysfunction, severe liver disease
  • Patients with high-dose corticosteroid therapy
  • prolonged corticosteroid or radiotherapy in the oral cavity
  • autoimmune diseases
  • Pregnant or breastfeeding women

Key Trial Info

Start Date :

August 6 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 15 2022

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT05267249

Start Date

August 6 2021

End Date

February 15 2022

Last Update

March 4 2022

Active Locations (1)

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Medical University of Graz

Graz, Styria, Austria, 8010