Status:

COMPLETED

Study to Confirm the Safety and Efficacy of Tegoprazan in Patients With Healed Erosive Reflux Disease

Lead Sponsor:

HK inno.N Corporation

Conditions:

Erosive Reflux Disease

Eligibility:

All Genders

19-80 years

Phase:

PHASE4

Brief Summary

This study is designed to evaluate the efficacy and safety of Tegoprazan 50mg, compared to Lansoprazole 30mg in patients with healed erosive reflux disease confirmed by endoscopy following oral admini...

Detailed Description

This is a double blind, radomized, active-controlled, phase 4 study. Subjects will be randomly assigned to one of the two treatment groups (Tegoprazan 50mg, Lansoprazole 30mg)

Eligibility Criteria

Inclusion

  • Erosive eshophagitis(LA calssfication Grades A to D) with in 30 days prior to Randomization
  • Those who have experienced heartburn symptoms within 7 days prior to Visit 1(screening date)

Exclusion

  • Unalbe to undergo upper GI endoscopy
  • H. pylori positive
  • Those who cannot write a clinical trial subject diary
  • Presence of esophageal stricture, ulcerated stricture, gastroesophageal varix, long segment Barrett's esophagus with \>3cm length(LSBE), eosinophilic oesophagitis, active digestive ulcer or gastric bleeding on an upper GI endoscopy

Key Trial Info

Start Date :

February 16 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 25 2022

Estimated Enrollment :

218 Patients enrolled

Trial Details

Trial ID

NCT05267743

Start Date

February 16 2021

End Date

May 25 2022

Last Update

July 29 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Wonkwang University Hospital

Iksan, Muwang-ro 895, South Korea, 54538