Status:
UNKNOWN
Independent Risk Factors Analysis and Model Construction For Recurrence After Radiofrequency/Microwave Ablation of Colorectal Cancer With Liver Metastases: a Retrospective, Multicenter Trial
Lead Sponsor:
The Central Hospital of Lishui City
Collaborating Sponsors:
Zhejiang Cancer Hospital
Zhejiang University
Conditions:
Colorectal Cancer With Liver Metastases
Eligibility:
All Genders
18+ years
Brief Summary
This study is a retrospective, multicenter clinical study. The main objective is to analyze the risk factors affecting the recurrence of colorectal cancer patients with liver metastases who received r...
Eligibility Criteria
Inclusion
- Age：older than 18 years；
- Patients with a single tumor diameter ≤5cm, no more than 3 tumor nodules, and the largest tumor diameter ≤3cm；
- Absence of vessel, bile duct and adjacent organ invasion and distant metastasis;
- The primary tumor of colorectal cancer has been resected, the liver metastases cannot be resected or the patient is unwilling to undergo surgery (clinical or pathological confirmation);
- Normal coagulation status and liver function child-pugh A or B;
- Liver metastases have not received other antitumor therapy after radiofrequency/microwave therapy (before disease progression);
- Routine laboratory tests were performed before the first RF/microwave treatment;
- Follow up for more than 12 months;
- Obtained free informed consent.
Exclusion
- Large tumor, or diffuse intrahepatic metastasis;
- Accompanied by vascular tumor thrombus or invasion of adjacent organs;
- The primary tumor of colorectal cancer has not been resected, with extrahepatic metastasis;
- Uncorrectable coagulation dysfunction and severe blood abnormalities, those with severe bleeding tendency;
- Intractable massive ascites, cachexia;
- Active infection, especially inflammation of the biliary system;
- Severe liver, kidney, heart, lung, brain and other major organ failure;
- Patients with impaired consciousness or unable to cooperate with treatment;
- Missing follow-up data.
Key Trial Info
Start Date :
March 12 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 12 2022
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT05268549
Start Date
March 12 2022
End Date
August 12 2022
Last Update
March 7 2022
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.