Status:
COMPLETED
18F-PBR06/Total Body PET Imaging in Patients With STEMI
Lead Sponsor:
RenJi Hospital
Conditions:
Myocardial Infarction
Eligibility:
All Genders
18-75 years
Brief Summary
The study will use 18F-PBR06/uExplorer to study the activation of macrophages and systemic perfusion in patients with ST-segment elevation myocardial infarction (STEMI) or stable angina (SA). Particip...
Detailed Description
The aim of our study is to explore the activation of macrophages in patients with ST-segment elevation myocardial infarction (STEMI) or stable angina (SA) using the 18 kDa translocator protein (TSPO) ...
Eligibility Criteria
Inclusion
- Aged 18-75 years old
- Diagnosed with STEMI, NSTEMI or suspected SA (ACC/AHA guidelines)
- Half male and half female
- Undergo CAG and PCI treatment if necessary (primary PCI for STEMI patients within12 hours after symptom onset)
- Written informed consents will be offered and signed by all participants
Exclusion
- History of myocardial infarction/vascular disease/heart failure/systemic inflammatory diseases before enrolment
- Patients who are pregnant/breastfeeding, or in a plan to have a baby during the year after CAG/PCI
- People under the age of 18 years old
- Inability to lie or maintain posture during the scanning procedure
Key Trial Info
Start Date :
July 8 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 10 2024
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT05269446
Start Date
July 8 2022
End Date
November 10 2024
Last Update
November 12 2024
Active Locations (1)
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1
Renji Hospital
Shanghai, China, 200127