Status:
UNKNOWN
The Predictive Value of Retinal Vascular Signs for Intracranial Artery Stenosis (RVS-ICAS)
Lead Sponsor:
Capital Medical University
Conditions:
Intracranial Stenosis
Eligibility:
All Genders
35+ years
Brief Summary
Intracranial artery stenosis (ICAS) is a leading cause of ischemic stroke worldwide, contributing to the global burden of stroke, particularly in the Asian population. However, there is no non-invasiv...
Detailed Description
Intracranial atherosclerosis stenosis (ICAS) is a leading cause of ischemic stroke worldwide, contributing to the global burden of stroke, particularly in the Asian population. Compared with the other...
Eligibility Criteria
Inclusion
- Age≥35
- Accept TCD examination and fundus examination
- Signed informed consent
Exclusion
- Non-atherosclerotic stenosis, such as arteritis, moyamoya disease, arterial dissection, vascular malformation, etc., which were clearly diagnosed.
- Intracranial space-occupying lesions
- Jugular vein and intracranial venous lesions
- Patients with severe cardiac, hepatic, renal disease.
- Life expectancy of less than 1 year due to co-morbid conditions.
- Known pregnancy (or positive pregnancy test), or breast-feeding.
- Pathological myopia fundus changes
- Glaucoma
- Refractive medium turbidity affects fundus observation
- Anterior macular membrane of both eyes
- Papilledema, optic neuritis and optic neuropathy
- Patients who have had internal eye surgery in the last six months (including fundus laser)
- Previous history of internal eye trauma
- Poor image quality of fundus and images
- Any condition which, in the judgment of the investigator, might increase the risk to the patient.
Key Trial Info
Start Date :
February 27 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2022
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT05270746
Start Date
February 27 2022
End Date
July 1 2022
Last Update
March 8 2022
Active Locations (2)
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1
Beijing Tiantan Hospital, Capital Medical University
Beijing, Fengtai District, China, 100070
2
Xuanwu hospital;Capital Medical University
Beijin, XI Cheng District, China, 100053