Status:

UNKNOWN

A Botanical Skin Care Regimen on Mild to Moderate Acne and the Microbiome

Lead Sponsor:

Integrative Skin Science and Research

Collaborating Sponsors:

Codex Beauty Corporation

Conditions:

Acne Vulgaris

Eligibility:

All Genders

15-45 years

Phase:

NA

Brief Summary

The purpose of this study is to analyze changes in acne and changes in the gut and skin microbiome with the use of a multi-step botanical skin care regimen in those with mild to moderate acne.

Eligibility Criteria

Inclusion

  • Subjects 15 years of age until 45 years of age.
  • The presence of mild to moderate acne based on investigator global assessment.

Exclusion

  • The presence of severe acne as noted by the investigator global assessment.
  • Those with a nut allergy.
  • Those who are unwilling to discontinue oral probiotic-based supplementation to meet the washout criteria prior to enrolling.
  • Those who are unwilling to discontinue topical antibiotics and topical benzoyl peroxide to meet the washout criteria prior to enrolling.
  • Individuals who are unwilling to discontinue vitamin E containing supplements during the washout and intervention.
  • Individuals who have been on an oral antibiotic for acne within the previous 1 month.
  • Individuals who are pregnant or breastfeeding.
  • Individuals who have changed any of their hormonal based contraception within 3 months prior to joining the study.
  • Oral supplementation that has nuts in it.
  • Use of isotretinoin within the three months prior to joining the study.
  • Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years.

Key Trial Info

Start Date :

March 7 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2023

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT05271487

Start Date

March 7 2022

End Date

March 1 2023

Last Update

March 9 2022

Active Locations (1)

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1

Integrative Skin Science and Research

Sacramento, California, United States, 95819