Status:
RECRUITING
Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries
Lead Sponsor:
Chonnam National University Hospital
Collaborating Sponsors:
Korean Cardiac Research Foundation
Abbott
Conditions:
Myocardial Infarction
Coronary Microvascular Dysfunction
Eligibility:
All Genders
19+ years
Brief Summary
To compare clinical outcomes of myocardial infarction with non-obstructive coronary arteries (MINOCA) according to the coronary microvascular dysfunction (CMD), evaluated by optical coherence tomograp...
Detailed Description
Background Approximately 5\~10% of patients with acute myocardial infarction (AMI) have been reported as myocardial infarction with non-obstructive coronary arteries (MINOCA) in the contemporary clini...
Eligibility Criteria
Inclusion
- Subject with age ≥19 years and acute myocardial infarction
- Rise and/or fall of cardiac troponin with one level \>99 percentile plus ischemic signs/symptoms
- Subject with non-obstructive coronary arteries
- \<50% diameter stenosis or
- fractional flow reserve (FFR) \>0.80 ③ Subject without previous history of coronary artery disease
- Subject who performed invasive coronary angiography within 24 hours after presentation ⑤ Subject who eligible for invasive and non-invasive coronary physiologic assessment
Exclusion
- Subject with obstructive coronary arteries
- Subject with alternate diagnosis including sepsis, pulmonary embolism, myocarditis, Takotsubo syndrome, spontaneous coronary dissection, and other cardiomyopathies.
- Subject with cardiogenic shock or cardiac arrest ④ Subject who has non-cardiac co-morbid conditions with life expectancy \<1 year ⑤ Subject or lactating women ⑥ Subject unable to provide consent
Key Trial Info
Start Date :
February 14 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2028
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT05272618
Start Date
February 14 2022
End Date
December 31 2028
Last Update
February 24 2025
Active Locations (1)
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1
Chonnam National University Hospital
Gwangju, South Korea, 61469