Status:
COMPLETED
Measurement of Lipogenic Flux by Deuterium Resolved Mass Spectrometry Via Non-invasive Breath Analysis
Lead Sponsor:
University Children's Hospital Basel
Collaborating Sponsors:
Swiss National Science Foundation
Fondation Botnar
Conditions:
De Novo Lipogenesis (DNL)
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This proof of concept- study is to measure de novo lipogenesis (DNL) non-invasively in exhaled breath in overnight-fasted humans by triggering feeding response by deuterium resolved mass spectrometry.
Detailed Description
The study objective is to measure the DNL by ingestion of a single oral dose of 70% 2H2O at 2 g/kg body-water. The subjects will consume a Yoghurt consisting of 300g of 'Excellence Joghurt Nature gezu...
Eligibility Criteria
Inclusion
- Healthy adult volunteers
- English speaking, or good knowledge of the English language
- Able to understand the study
- Able to give informed consent
Exclusion
- Current pregnancy
Key Trial Info
Start Date :
May 11 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2022
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT05274334
Start Date
May 11 2022
End Date
September 30 2022
Last Update
November 4 2022
Active Locations (1)
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1
University Children's Hospital Basel (UKBB)
Basel, Switzerland, 4056