Status:

COMPLETED

CPT-L to Improve Outcomes for Individuals With HIV and PTSD

Lead Sponsor:

Medical University of South Carolina

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

Conditions:

PTSD

Hiv

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study plans to adapt and examine the acceptability and feasibility of an evidence-based PTSD treatment that has reduced other HIV transmission behavior (e.g., sexual risk), Cognitive Processing T...

Detailed Description

The prevalence of trauma exposure, and post-traumatic stress disorder (PTSD) in particular, among individuals living with HIV (30-74%) is higher than the general population (7-10%). Individuals with c...

Eligibility Criteria

Inclusion

  • Individuals that are 18 years and older
  • Linked with and/or eligible for treatment at a Ryan White clinic in South Carolina.
  • Participant meets clinically significant threshold of DSM-V PTSD criteria as determined by a Clinician Administered PTSD Scale for DSM-5 (CAPS-5) clinical interview.
  • No changes in psychotropic medication within 4 weeks of study enrollment.
  • Able to speak, read, and write English.
  • Meet at least one of the following HIV care criteria:
  • Diagnosed with HIV in the last 3 months;
  • Detectable viral load in the last 12 months;
  • Failed to show up for or missed 1 or more HIV care appointments in the past 12 months;
  • Last HIV care visit was more than 6 months ago;
  • Self-reporting less than 90% ART adherence in the past 4 weeks.
  • A score of at least 10 on the Montreal Cognitive Assessment test (MoCA)

Exclusion

  • Evidence of significant cognitive impairment as assessed by the Montreal Cognitive Assessment Test (MoCA; in the severe range).
  • Evidence of developmental delays, or pervasive developmental disorder, or active suicidal or homicidal ideations.
  • Evidence of psychotic symptoms (e.g., active hallucinations, delusions, impaired thought processes).

Key Trial Info

Start Date :

July 13 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 30 2024

Estimated Enrollment :

41 Patients enrolled

Trial Details

Trial ID

NCT05275842

Start Date

July 13 2022

End Date

August 30 2024

Last Update

March 4 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Medical University of South Carolina

Charleston, South Carolina, United States, 29425

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