Status:
RECRUITING
Effect of Circadian Rhythm and Physical Exercise in Overweight Type 1 Diabetes Patients
Lead Sponsor:
Karolinska Institutet
Conditions:
Type 1 Diabetes
Overweight
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
Cardiometabolic risk in patients with abdominal obesity and type 1 diabetes can be moderated by life style modifications. There is an intimate link between gene regulation and circadian rhythm in medi...
Detailed Description
High intensity interval training (HIIT) is a promising intervention for lifestyle treatment in type 1 diabetes. In spite of the interplay between circadian rhythms and exercise, the time of day in whi...
Eligibility Criteria
Inclusion
- BMI 25-30
- type 1 diabetes or healthy subjects
Exclusion
- nicotine usage,
- cardiovascular disease (CVD),
- blood pressure \>160/95,
- pregnancy,
- treatment with other pharmaceutical drugs than insulin, stable dose of thyroid hormone, statins, and antihypertensive drugs (excluding beta blockers).
- Additional exclusion criteria for diabetes subjects:
- diabetes duration less than 6 months,
- proliferative or severe non-proliferative retinopathy,
- chronic kidney disease with glomerular filtration rate (GFR) \<60 ml/min,
Key Trial Info
Start Date :
May 18 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 31 2026
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05277532
Start Date
May 18 2022
End Date
October 31 2026
Last Update
October 15 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Ersta sjukhus
Stockholm, Sweden, 11691