Status:
UNKNOWN
Autonomic Nervous System Dysfunction in Patients With End-stage Kidney Disease
Lead Sponsor:
Aristotle University Of Thessaloniki
Conditions:
Kidney Failure, Chronic
Eligibility:
All Genders
18+ years
Brief Summary
The prevalence of autonomic nervous system (ANS) dysfunction in patients with end-stage kidney disease (ESKD) is considered to be increased. The uraemic environment, as well as the high incidence of c...
Detailed Description
This is an observational study performed in the Department of Nephrology, Hippokration Hospital, Thessaloniki, Greece. For the purposes of this study, adult patients (\>18 years) with ESKD being treat...
Eligibility Criteria
Inclusion
- Age \>18 years
- ESKD individuals treated with either hemodialysis (standard thrice weekly schedule) or peritoneal dialysis for at least 3 months
- Provision of informed written consent
Exclusion
- Antihypertensive treatment modifcation during one month prior to study enrollment
- Modification of treatment for neurological disorders one month prior to study enrollment
- Active malignant disease or other comorbidity with poor prognosis
- History of neurological disorders (e.g. Parkinson's disease, multiple sclerosis, etc) that cause primary ANS dysfunction
- History of ANS dysfunction secondary to diabetes mellitus, amyloidosis, autoimmune disorders, etc.
- Active infection or relevant inter-current illness.
- History of drug or alcohol abuse or severe mental disorder
Key Trial Info
Start Date :
April 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2022
Estimated Enrollment :
78 Patients enrolled
Trial Details
Trial ID
NCT05278702
Start Date
April 1 2021
End Date
December 31 2022
Last Update
March 14 2022
Active Locations (1)
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1
Department of Nephrology, Hippokration Hospital
Thessaloniki, Greece, 54642