Status:

COMPLETED

A Phase 3b/4 Randomised Trial of 3 Doses of Protein-based Covid-19 Vaccine (SpikoGen)

Lead Sponsor:

Vaxine Pty Ltd

Collaborating Sponsors:

Australian Respiratory and Sleep Medicine Institute

Conditions:

COVID-19

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

This study will determine the immunogenicity of Spikogen in vaccine naïve individuals. Spikogen will be administered as two doses 1 month apart with a third booster dose either 1 or 3 months after the...

Detailed Description

The SARS-CoV-2 outbreak has caused millions of deaths globally. It has a particularly high mortality rate in elderly people and those with chronic disease where mortality rates can be as high as 20-30...

Eligibility Criteria

Inclusion

  • Able to provide written informed consent
  • Males or females\* 18 years of age or older
  • Understand and are likely to comply with planned study procedures and be available for all study visits.
  • Have not previously had a Covid-19 vaccine and do not intend to have a non-study Covid-19 vaccine within the next 6 months

Exclusion

  • History of Covid-19 vaccination.
  • History of serious vaccine allergy.
  • Pregnancy1
  • Have received an experimental agent within 30 days prior to the study vaccination or expect to receive another experimental agent during the trial reporting period.
  • Any medical, social or mental condition which, in the opinion of the investigator, would be detrimental to the subjects or the study.

Key Trial Info

Start Date :

August 15 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2023

Estimated Enrollment :

39 Patients enrolled

Trial Details

Trial ID

NCT05279456

Start Date

August 15 2022

End Date

December 31 2023

Last Update

September 17 2025

Active Locations (1)

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1

ARASMI

Adelaide, South Australia, Australia, 5042