Status:

COMPLETED

Dual Use of ENDS and Combustible Cigarettes

Lead Sponsor:

Brown University

Collaborating Sponsors:

National Institute on Drug Abuse (NIDA)

Conditions:

Smoking, Cigarette

Electronic Cigarette Use

Eligibility:

All Genders

21-34 years

Phase:

NA

Brief Summary

This study investigates the degree to which shared behavioral processes underlie combustible cigarette (CC) and electronic nicotine delivery system (ENDS) use in young adult dual users of these produc...

Detailed Description

This project will enroll 80 young adults who regularly use both CC and ENDS. At the start of the study, participants will provide informed consent; biological indicators and self-report measures will ...

Eligibility Criteria

Inclusion

  • Age 21 to 34 (inclusive)
  • English-speaking at an 8th grade level
  • Any self-reported past 7-day use of both ENDS and cigarettes
  • Self-identification as a regular ENDS and combustible cigarette user OR use of cigarettes and e-cigarettes on at least 6 of the past 7 days including at least 3 days of using each product;
  • Smoking status confirmed via breath CO \>= 6 ppm112 or NicAlert test of urine cotinine (level \>= 3)
  • Smartphone ownership.

Exclusion

  • Intention to quit smoking or vaping during the next 30 days
  • Intention to travel during next 30 days
  • Current alcohol dependence (based on MINI)
  • Urine-screened or past month illicit substance use other than marijuana (amphetamine, cocaine, methamphetamine, opioids, benzodiazepines
  • Pregnant (due to toxicity of tobacco products)
  • Current psychosis, mania, or suicidal ideation (based on MINI).

Key Trial Info

Start Date :

December 14 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 20 2025

Estimated Enrollment :

82 Patients enrolled

Trial Details

Trial ID

NCT05280535

Start Date

December 14 2022

End Date

May 20 2025

Last Update

September 18 2025

Active Locations (1)

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1

Center for Alcohol and Addiction Studies

Providence, Rhode Island, United States, 02903