Status:

COMPLETED

Home-based tDCS for Prevention of Suicidal Ideation

Lead Sponsor:

University of Rochester

Collaborating Sponsors:

Brain & Behavior Research Foundation

Conditions:

Suicidal Ideation

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Risk for suicide is elevated in the period after discharge from hospital among adults with major affective disorder. The primary objective of this study is to investigate the feasibility of delivering...

Eligibility Criteria

Inclusion

  • age between 18 and 65 years
  • diagnosis of mood or bipolar disorder registered in the electronic hospital medical record
  • history of suicidal ideation and/or suicidal behavior at the time of admission registered in the electronic hospital medical record
  • absent of suicidal ideation at the time of enrollment (defined as questions 1 and 2 of the C-SSRS answered "no")
  • ability and willingness to provide information and permission to contact at least one person in the case of a need to contact them to promote subject safety or inability to reach the subject for follow-up
  • a living situation with access to a private space suitable for the administration of the RS-tDCS sessions in the next three weeks
  • agree to use a medically acceptable form of birth control while receiving the treatment if you are an individual able to become pregnant
  • living in Monroe County region, as this is the area covered by the Mobile Crisis Team, a URMC psychiatric emergency team serving anyone within Monroe County
  • device or computer with internet access for a URMC-approved remote RS-tDCS supervision
  • ability to manage proper use of the device in a practice session

Exclusion

  • acute psychiatric instability or substance abuse (e.g., psychotic symptoms, alcohol misuse in the previous three months, use of any illicit drugs in the previous three months)
  • unstable medical condition with reduction of functional capacity
  • history of epilepsy or seizures in the last year
  • history of neurodegenerative diseases registered in the electronic hospital medical record
  • presence of or implanted any ferromagnetic metal in the head or the neck
  • pregnant or breastfeeding or willingness to become pregnant in the next month
  • history of head trauma (e.g., head injury, brain injury) or neurosurgery
  • history of skin disorder or sensitive skin area near stimulation locations
  • the presence of pacemaker
  • current treatment with electroconvulsive therapy or transcranial magnetic stimulation

Key Trial Info

Start Date :

September 21 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 11 2024

Estimated Enrollment :

33 Patients enrolled

Trial Details

Trial ID

NCT05280756

Start Date

September 21 2023

End Date

June 11 2024

Last Update

May 7 2025

Active Locations (1)

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1

University of Rochester

Rochester, New York, United States, 14642