Status:
TERMINATED
Effects of Exercise & Tart Cherry Ingestion on Heat Acclimation and Gut Microbiome
Lead Sponsor:
Ohio University
Conditions:
Heat Acclimation and Thermotolerance
Eligibility:
MALE
18-55 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether tart cherry supplementation effects thermotolerance and heat acclimation in human subjects exposed to exercise/heat stress. Specific Aim I. To determ...
Detailed Description
10 recreationally trained cyclists will be recruited and will complete the study in counter-balanced randomized order (5 will start with placebo and 5 will start with tart cherry juice, then have a 4 ...
Eligibility Criteria
Inclusion
- Male
- 18-55 years old
- Recreational cyclists (\>150 minutes per week of cycling exercise)
- VO2max \>60th percentile according to ACSM
Exclusion
- Previous episode of heat illness, such as heat syncope, heat exhaustion or heat stroke
- Known cardiopulmonary disease, metabolic disorders, Parkinsons Disease, or multiple sclerosis or other autonomic nervous system conditions
- diagnosed with or being treated for arthritis or any inflammatory condition (such as Lupus, gout, or Sjogrens syndrome)
- Known or suspected orthostatic hypotension or low blood pressure
- Known issues with cooling or sweating
- currently smoke or quit smoking less than one year ago
- not willing to self-insert a flexible, thin (3 mm) vinyl rectal probe and maintain this position throughout all exercise sessions.
- not willing to have blood drawn pre-supplementation and 4 times during heat stress test trials (a total of 10 times during the study).
- not willing to provide a stool sample pre- and post-heat stress tests (4 total samples).
- allergy to cherries or food dyes
Key Trial Info
Start Date :
January 26 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2023
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT05281198
Start Date
January 26 2022
End Date
April 30 2023
Last Update
October 16 2023
Active Locations (1)
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1
Ohio University Exercise Physiology Lab
Athens, Ohio, United States, 45701