Status:
COMPLETED
Effects of Trunk Postural Change on CO2 Removal Efficiency in ARDS Patients: Quasi-experimental Study
Lead Sponsor:
Clinica las Condes, Chile
Conditions:
ARDS
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
OBJECTIVES: The trunk inclination from semirecumbent to lying supine improves lung mechanics and reduces end-expiratory lung volume in Acute Respiratory Distress Syndrome (ARDS) patients. Besides, it ...
Detailed Description
The role of trunk inclination in the lying position and its physiological effects have been extensively studied in patients with acute respiratory distress syndrome (ARDS). Consistently, driving pres...
Eligibility Criteria
Inclusion
- Over 18 years old
- Admitted to Intensive Care with mild, moderate, or severe ARDS according to the Berlin classification
- Less than 72 hours of connection to mechanical ventilation.
- Depth Sedation-analgesia.
- Acceptance by the legal representative to participate in the study.
Exclusion
- Pleural tube - bronchopulmonary fistula.
- Prone position
- Hypovolemic shock with active bleeding.
- Intracranial hypertension.
- Gastric residue greater than 300 ml in the last 6 hours
- Hemodynamic instability that requires a progressive increase in the dose of vasopressors
- Temperature variations greater than 0.5 ° C in the last 2 hours
- Acute heart failure
- Chronic respiratory disease (FEV1 \<50% predicted).
- Patients who do not have an arterial line.
Key Trial Info
Start Date :
April 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2022
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT05281536
Start Date
April 1 2021
End Date
September 30 2022
Last Update
November 17 2022
Active Locations (2)
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1
Clínica Las Condes
Santiago, Santiago Metropolitan, Chile, 13114
2
Martín Hernán Benites
Santiago, Santiago Metropolitan, Chile, 7550000