Status:

COMPLETED

Evaluation of Galectin-3 Levels in GCF And Saliva of Patients With Different Periodontal Diseases

Lead Sponsor:

Cairo University

Conditions:

Periodontal Diseases

Eligibility:

All Genders

18-60 years

Brief Summary

The aim of this study is to assess the levels of galectin-3 in the GCF and saliva in patient with gingivitis and patient with stage III periodontitis.

Detailed Description

The aim of this study is to assess the levels of galectin-3 in the GCF and saliva in patient with gingivitis and patient with stage III periodontitis. This study will be conducted in the Oral Medicin...

Eligibility Criteria

Inclusion

  • For healthy group: individuals with less than 10% bleeding on probing area, having a probing depth less than 4mm and no loss of attachment were included in the study.
  • For the gingivitis group: individuals with 10% or more bleeding on probing area, having a probing depth of less than 4mm and no attachment loss.
  • For the periodontitis group that has not received periodontal treatment in the last 6 months
  • For the periodontitis group: individuals with 30% or more bleeding on probing area, at least 2 teeth not adjacent to each quarter jaw with a depth of 5 mm or more and 4 mm or more attachment loss, coronal 1/3 and more on radiography (horizontal and / or vertical) bone loss.
  • Presence of a minimum of 15 natural teeth.

Exclusion

  • Individuals with any known systemic disease.
  • Pregnant and lactating women.
  • Individuals that received periodontal treatment within the last 6 months.
  • Individuals with a history of systemic antibiotics and anti-inflammatory drugs within the last 3 months.
  • Former or current smokers.

Key Trial Info

Start Date :

January 22 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 15 2023

Estimated Enrollment :

66 Patients enrolled

Trial Details

Trial ID

NCT05281796

Start Date

January 22 2022

End Date

August 15 2023

Last Update

November 24 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Cairo university Faculty of dentistry

Cairo, Egypt, 11311