Status:

UNKNOWN

Involved Nodal Irradiation vs Involved Field Irradiation After Cth in Ttt of Early Stages HDs

Lead Sponsor:

Assiut University

Conditions:

Hodgkin Lymphoma

Eligibility:

All Genders

18-75 years

Brief Summary

determine the early toxicity and loco-regional control comparing outcome of radiothrapy rither by using INRT or IFRT in treatment of early stage hodgkin lymphoma determine progression-free survival a...

Detailed Description

Hodgkin lymphoma (HL) is one of the most frequent lymphomas in the Western world, with an annual incidence of about 3 cases per 100,000 persons. This lymphoid malignancy involves peripheral lymph node...

Eligibility Criteria

Inclusion

  • Histologically proven Hodgkin's Lymphoma, with exclusion of the nodular lymphocyte predominant subtybe
  • Clinical stage I or II, only supra-diaphragmatic nodes, both favorable and unfavorable prognostic subsets
  • Previously untreated.
  • Age: between 18 and 75 years.
  • Good general condition(WHO performance status 0-2).
  • Free of concurrent disease.

Exclusion

  • Patients with impaired heart, lung, liver, or kidney function.
  • Previous malignant diseases or HIV-positive status
  • Patient with advanced or infra-diaghragmatic Hodgkin's disease
  • Pregnant or lactating women
  • Patient with prior irradiation to the neck and thorathic region

Key Trial Info

Start Date :

May 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 1 2025

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT05284396

Start Date

May 1 2022

End Date

October 1 2025

Last Update

March 17 2022

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Involved Nodal Irradiation vs Involved Field Irradiation After Cth in Ttt of Early Stages HDs | DecenTrialz