Status:
RECRUITING
Rheolytic Thrombectomy For Acute Deep Vein Thrombosis Of Whole Lower Limb
Lead Sponsor:
RenJi Hospital
Collaborating Sponsors:
First People's Hospital of Hangzhou
The First Affiliated Hospital with Nanjing Medical University
Conditions:
Deep Vein Thrombosis
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Ipsilateral popliteal venous the most common access for pharmacomechanical thrombectomy (PMT) in the treatment of acute deep venous thrombosis (DVT), but the result was not satisfactory. The investiga...
Detailed Description
Acute deep venous thrombosis (DVT) with whole lower limb involved is associated with significant post thrombotic morbidity. Both of deep venous occlusion and valvar reflux increase the risk for develo...
Eligibility Criteria
Inclusion
- Age between 18-80 years old;
- Acute DVT with clinical symptoms occurred less than 14 days since the onset of disease;
- DVT with thrombosis involving the iliac vein, common femoral vein, distal popliteal vein, and/or calf vein;
- Informed consent signed by patients.
Exclusion
- Patients with the previous history of the same side of lower-limb DVT;
- Patients with plasma Creatinine level greater than 180umol/L;
- Patients who are contraindicated to thrombolysis;
- Patients with inferior vena cava thrombosis;
- Patients who are known to be allergic to heparin, low molecular weight heparin, or contrast agent;
- Patients who have participated in a clinical trial in the past three months;
- Women during pregnancy and lactation
- Patients with other diseases that may cause difficulty in the study or significantly shorten the life expectancy of patients (\<2 years);
- Patients with autoimmune thrombopathy or thrombocytopenia (platelets \< 80·10⁹/L);
- Patients who are unable or unwilling to participate in the study.
Key Trial Info
Start Date :
September 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT05286710
Start Date
September 1 2022
End Date
December 31 2027
Last Update
May 15 2025
Active Locations (1)
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1
Renji Hospital
Shanghai, Shanghai Municipality, China, 200127