Status:

RECRUITING

International Multicentric Study ARON-1

Lead Sponsor:

Hospital of Macerata

Conditions:

Metastatic Renal Cell Carcinoma (mRCC)

Eligibility:

All Genders

18+ years

Brief Summary

The ARON-1 Study is designed as an International Multicentric Retrospective Study to collect global experiences with the use of immuno-combinations in patients with metastatic RCC. Two Supplementary ...

Eligibility Criteria

Inclusion

  • Patients aged \>18y
  • Cytological or Histologically confirmed diagnosis of clear cell or non-clear cell RCC
  • Histologically or radiologically confirmed diagnosis of metastatic disease
  • First-line treatment with nivolumab plus ipilimumab or nivolumab plus cabozantinib or pembrolizumab plus axitinib or pembrolizumab plus lenvatinib or avelumab plus axitinib or atezolizumab plus bevacizumab

Exclusion

  • Patients without histologically confirmed diagnosis of RCC
  • Patients without histologically or radiologically confirmed metastatic disease
  • Patients treated with immuno-combinations not included in the list reported in the Inclusion Criteria Section

Key Trial Info

Start Date :

March 10 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 30 2027

Estimated Enrollment :

1220 Patients enrolled

Trial Details

Trial ID

NCT05287464

Start Date

March 10 2022

End Date

September 30 2027

Last Update

November 26 2025

Active Locations (1)

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1

Ospedale di Macerata, UOC Oncologia

Macerata, Macerata, Italy, 62100