Status:
UNKNOWN
Quantitative Analysis of 18F-FAPI Dynamic PET/CT for Accurate Differential Diagnosis of MLN of ESCC
Lead Sponsor:
Fifth Affiliated Hospital, Sun Yat-Sen University
Collaborating Sponsors:
Sun Yat-sen University
The First Affiliated Hospital of Guangzhou Medical University
Conditions:
Esophageal Squamous Cell Carcinoma
Benign Lymph Node Neoplasm
Eligibility:
All Genders
18-85 years
Brief Summary
Patients diagnosed with esophageal squamous cell carcinoma based on clinicopathology, laboratory examination and imaging criteria were selected as the research subjects, and compared with conventional...
Detailed Description
Esophageal cancer (EC) is the eighth most common cancer in the world. Like most other cancers, the occurrence and progression of ESCC is a multi-stage process that closely affects the treatment approa...
Eligibility Criteria
Inclusion
- Esophageal squamous cell carcinoma was diagnosed according to gastroscopy and pathological diagnostic criteria;
- Age above 18 years old, less than 85 years old, no gender restriction;
- Untreated patients who have not received surgery, chemotherapy, biotherapy or radiotherapy;
- Laboratory examination:
- (1) General physical condition score ECOG: 0-2; (2) No dysfunction of main organs; (3) Oxygen partial pressure ≥ 10.64kPa; (4) WBC ≥ 4×109 L-1; (5) Routine blood hemoglobin ≥ 9.5 g· DL-1; (6) The absolute count of neutrophils ≥ 1.5×109 L-1; (7) Platelet count ≥ 100×109 L-1; (8) Total bilirubin ≤ 1.5 times the upper limit of normal value; (9) Creatinine ≤ 1.25 times the upper limit of normal value; (10) Creatinine clearance rate ≥ 60 mL ·min-1;
- 5\. Can obtain complete follow-up information, understand the situation of this study and sign the informed consent.
Exclusion
- Has had any other malignant tumor within 5 years;
- Nursing and/or pregnant women;
- Patients with severe bleeding tendency;
- Recent severe hemoptysis, severe cough, dyspnea or patients cannot cooperate;
- Severe emphysema, pulmonary congestion and cor pulmonale;
- In the opinion of the Investigator, the subject may not be able to complete the study or comply with the requirements of the study (for administrative or other reasons).
Key Trial Info
Start Date :
March 10 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05287880
Start Date
March 10 2022
End Date
December 31 2023
Last Update
March 18 2022
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