Status:
COMPLETED
The Different Response of Endocrine Hormones to Hypoglycemia in Patients With Type 1 or Type 2 Diabetes
Lead Sponsor:
Nanjing First Hospital, Nanjing Medical University
Conditions:
Diabetes
Eligibility:
MALE
18-50 years
Brief Summary
Endocrine hormones, not only blood glucose responsive hormones, but also sexual hormones, thyroid hormones, growth hormones and so on, may have response and activites in hypoglycemia. However, the dif...
Detailed Description
This study will observe the changes of insulin, C-peptide, glucagon, growth hormone, IGF-1, ACTH, cortisol, thyroid function, sexual hormone in newly diagnosed men with type 2 and type 1 diabetes mell...
Eligibility Criteria
Inclusion
- \- Patients
- newly diagnosed male patients with type 1 or type 2 diabetes (diagnostic criteria of World Health Organization)
- aged 18-50 years
- has not been treated with any hypoglycemic drugs
- HbA1c\>9% Normal subjects: healthy and had no known illness
Exclusion
- patients with insulin allergy.
- any history of hypoglycemic agent intake or were presently taking hypoglycemic agents
- any abnormality in liver or kidney function on blood and urine investigations
- any history of systemic corticosteroid use in 3 months
- any recent infections or acute medical events
- any other obvious conditions or associated diseases determined by the researcher: such as severe cardiopulmonary diseases, endocrine diseases, neurological diseases, tumors and other diseases, other pancreatic diseases, history of mental diseases.
Key Trial Info
Start Date :
January 6 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 16 2022
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT05290207
Start Date
January 6 2022
End Date
September 16 2022
Last Update
May 31 2023
Active Locations (1)
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1
Nanjing First Hospital, Nanjing Medical Univesity
Nanjing, China