Status:

COMPLETED

Modulation of Emotion Perception in Humans Via Amygdala Stimulation

Lead Sponsor:

Dartmouth-Hitchcock Medical Center

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

Conditions:

Refractory Epilepsy

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study will enroll patients with epilepsy who are being evaluated for epilepsy surgery and have intracranial EEG electrodes. In this study, the aim is to record brain signals from areas important ...

Detailed Description

One to two study tasks will be performed by each participant to help us understand how the brain processes emotion and how stimulation effects emotional processing. These study tasks will last up to ...

Eligibility Criteria

Inclusion

  • Age of 18 years or older
  • FSIQ 75 and above or any equivalent test of generalized intelligence as determined by the PI to adequately predict engagement in the task
  • Able to give independent consent for participation in the study

Exclusion

  • Additional neurological disorders (such as dementia, stroke, brain tumor, etc.)
  • Any psychiatric condition that would limit their ability to provide consent and/or perform study tasks within normal limits. This would be based on presurgical psychiatric assessment.
  • Anything else, that in the opinion of the principal investigator, might preclude them from participating in the study

Key Trial Info

Start Date :

March 31 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 16 2024

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT05292183

Start Date

March 31 2022

End Date

February 16 2024

Last Update

September 22 2025

Active Locations (1)

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Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, United States, 03776