Status:
COMPLETED
Effect of EEG-guided General Anesthesia on Cumulative Dose of Norepinephrine
Lead Sponsor:
Universitätsklinikum Hamburg-Eppendorf
Conditions:
Hypotension
Eligibility:
All Genders
45+ years
Phase:
NA
Brief Summary
Intraoperative hypotension is common in patients having non-cardiac surgery under general anesthesia and is associated with major postoperative complications including myocardial injury, AKI, and deat...
Eligibility Criteria
Inclusion
- We will include consenting patients ≥45 years scheduled for elective vascular surgery under general anesthesia if:
- surgery is expected to last at least 60 min AND
- the estimated blood loss during surgery is less than 1000 mL AND
- intraarterial blood pressure monitoring (arterial catheter) is planned during surgery
- We will not include patients with previous transplantation of kidney, liver, heart, or lung and those who are septic (according to current Sepsis-3 definition). And we will not include patients with American Society of Anesthesiologists' physical status V and VI, or pregnancy.
- We will exclude patients after randomization if they were treated with vasopressors others than norepinephrine during surgery.
- Written informed consent will be obtained from all patients prior to study inclusion.
Exclusion
Key Trial Info
Start Date :
February 15 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 16 2023
Estimated Enrollment :
110 Patients enrolled
Trial Details
Trial ID
NCT05293288
Start Date
February 15 2022
End Date
August 16 2023
Last Update
November 18 2023
Active Locations (1)
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1
University Medical Center Hamburg-Eppendorf
Hamburg, Germany, 20251