Status:
COMPLETED
Assessment of an Exhaled Breath Test to Detect Bronchiectasis
Lead Sponsor:
Shanghai Pulmonary Hospital, Shanghai, China
Conditions:
Bronchiectasis
Eligibility:
All Genders
18-90 years
Brief Summary
To investigate whether the breath test is able to detect bronchiectasis using breathomics. This study was conducted with a prospective specimen collection, evaluator-blinded, case-controlled clinical ...
Detailed Description
Bronchiectasis is a chronic airway inflammation with irreversible expansion of bronchial walls, which is characteristic by chronic cough, mucinous sputum, dyspnea and wheezing. High resolution CT (HRC...
Eligibility Criteria
Inclusion
- BE Patients were recruited according to the following inclusion criteria: (1) Age\>18 years; (2) the diagnosis of BE was according to European Respiratory Society guidelines for the management of adult bronchiectasis; (3) Willing to join in and sign the informed consent form.
- Healthy control subjects were recruited according to the following inclusion criteria:(1) Age\>18 years; (2) No history of any lung disease (according to pulmonary imaging and physical examinations); (3) Willing to join in and sign the informed consent form.
- Unhealthy control subjects were recruited according to the following inclusion criteria: (1) Age\>18 years; (2) The diagnosis of ILD was according to HRCT and clinical symptoms by two experts' consensus; (3) The diagnosis of Sarcoidosis (SA) was according to American Thoracic Society Clinical Practice Guideline;(4) Willing to join in and sign the informed consent form.
Exclusion
- (1) Patients combined with serious comorbidities (chronic renal failure, hepatic disease, etc.); (2) Patients who are diagnosed with asthma, pneumonia, malignant tumor, and COPD; (3) Women who are pregnant or preparing for pregnancy or breastfeeding; (4) Participated in other clinical trials within three months; (5) Refused to join in and sign the informed consent form.
Key Trial Info
Start Date :
July 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 20 2023
Estimated Enrollment :
544 Patients enrolled
Trial Details
Trial ID
NCT05293314
Start Date
July 1 2022
End Date
May 20 2023
Last Update
November 19 2024
Active Locations (1)
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1
Shanghai pulmonary hospital
Shanghai, Shanghai Municipality, China, 200433