Status:
UNKNOWN
Comparison Of Deep Versus Moderate Neuromuscular Blockade on Intra-Operative Blood Loss During Spinal Surgery
Lead Sponsor:
Assiut University
Conditions:
Spine Fracture
Eligibility:
All Genders
18-65 years
Phase:
EARLY_PHASE1
Brief Summary
Reduction of intra-operative blood loss
Detailed Description
Spine surgery is usually performed using a posterior approach with the patient in the prone position, but on the other hand this position causes venous engorgement in the back and increases bleeding w...
Eligibility Criteria
Inclusion
- Age 18- 65 years.
- American Society of Anesthesiologists physical status classification (ASA) I - III
- Patients scheduled for posterior lumbar interbody fusion (2-level or 3-level).
Exclusion
- Urgent or emergency case or re-operation.
- History of pre-operative anticoagulant medication or an indication for peri-operative anticoagulant medication.
- ASA classification more than III.
- Age less than 16 years.
- Reduced left and right ventricular function (ejection fraction \<40%).
- Previous respiratory disease or a diagnosed neuromuscular disorder.
- Pre-operative dysrhythmia.
- Allergy to neuromuscular blocking agents.
- Family history of malignant hyperthermia.
- Decreased renal function (serum creatinine level more than twice the normal range, urine output \<0.5 ml kg/h, glomerular filtration ratio \<60 ml/ h).
Key Trial Info
Start Date :
April 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 30 2023
Estimated Enrollment :
88 Patients enrolled
Trial Details
Trial ID
NCT05294926
Start Date
April 1 2022
End Date
March 30 2023
Last Update
March 24 2022
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